Gene information
Official symbol TAC1
Official full name tachykinin precursor 1
Gene type protein-coding gene
Chromosome7q21.3
Alias symbolNPK
Previous symbolTAC2; NKNA
Gene familyTachykinin precursors
Resources
Entrez Gene 6863
HGNC HGNC:11517
Ensembl ENSG00000006128
Vega OTTHUMG00000154069
UCSC uc003uop.5
GO terms: 21 records
GO Description Category LogP Number of genes Detail
GO:0001664 G protein-coupled receptor binding GO Molecular Functions -22.7408810 35 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0007218 neuropeptide signaling pathway GO Biological Processes -4.86030435 9 More
GO:0007268 chemical synaptic transmission GO Biological Processes -4.44678751 35 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0009582 detection of abiotic stimulus GO Biological Processes -2.39356289 13 More
GO:0019233 sensory perception of pain GO Biological Processes -10.7642352 20 More
GO:0030424 axon GO Cellular Components -6.14132550 54 More
GO:0033555 multicellular organismal response to stress GO Biological Processes -7.79385832 16 More
GO:0043025 neuronal cell body GO Cellular Components -9.18558636 52 More
GO:0044297 cell body GO Cellular Components -11.7206640 62 More
GO:0044703 multi-organism reproductive process GO Biological Processes -20.5752550 28 More
GO:0044706 multi-multicellular organism process GO Biological Processes -20.0155761 28 More
GO:0048265 response to pain GO Biological Processes -4.73205562 8 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071855 neuropeptide receptor binding GO Molecular Functions -7.75588867 8 More
GO:0098916 anterograde trans-synaptic signaling GO Biological Processes -4.44678751 35 More
GO:0099536 synaptic signaling GO Biological Processes -6.00976162 42 More
GO:0099537 trans-synaptic signaling GO Biological Processes -5.17038357 38 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
Drug-Gene interaction
view
Related drugs: 22 records
Drug name Interaction type Source PMID View
baclofen NCI 2467977 view
chlorhexidine NCI 14631229 view
digoxin NCI 1717629 view
ether NCI 2421032 view
etidronic acid NCI 16133581 view
famotidine NCI 12495560 view
furosemide NCI 2048822 view
ginger NCI 1282221 view
gossypol NCI 2887120 view
haloperidol NCI 6166743 view
loratadine NCI 12836989055977 view
methoxsalen NCI 9430496 view
mexiletine NCI 7686682 view
naltrexone NCI 7536308 view
nizatidine NCI 12495560 view
omeprazole NCI 1568450316259735 view
protoporphyrin NCI 9677143 view
puromycin NCI 14623771 view
reserpine NCI 61743526183051 view
sulindac NCI 1707646 view
terfenadine NCI 1696438 view
wortmannin NCI 9850167 view
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
protachykinin-1 proteomics major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Ng LL et al. J Am Coll Cardiol. 2014
protachykinin-1 proteomics death;recurrent myocardial infarction[prognosis (bad)] acute myocardial infarction Ng LL et al. J Am Coll Cardiol. 2014
protachykinin-1 proteomics death;heart failure[prognosis (bad)] acute myocardial infarction Ng LL et al. J Am Coll Cardiol. 2014
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